ANTI INFLAMMATION
Delphinol superiorfull-spectrum antioxidant orac potency
The transcription factor nuclear factor-kB (NF-kB) is activated by oxidative stress and pro-inflammatory stimuli and controls the expression of numerous genes involved in the inflammatory response. Dampening NF-kB activation and thereby limiting the inflammatory response have been suggested as a potential strategy to prevent chronic inflammatory diseases.
Free Radical Oxidative Stress
Delphinol anti-inflammatory effect in vivo model
Inflammation was induced in Sprague Dawley rats using 1% carrageenan. The diameter of the injure was measure as area under the curve (AUC0-6) was calculated
Treatment with anthocyanidins rich in delphinidins significantly
Delphinol delphinidins protect skins cells from uvb radiation damage
Inflammation was induced in Sprague Dawley rats using 1% carrageenan.
The diameter of the injure was measure as area under the curve (AUC0-6) was calculated
Delphinol lowers oxidised ldl cholesterol in cigarette smokers
The antioxidant virtues of DELPHINOL® have been demonstrated in a double-blind, placebo-controlled, cross-over study with 50 over-weight cigarette smokers.
Subjects received 150 mg Delphinol capsules, three times a day, or placebo. There was a wash-out period of four weeks during which the subjects crossed- over to opposite regimen.
- F2 isoprost ane is a validated marker for oxidative stress in humans.
- isoprostanes develop when reactive oxygen radicals oxidise poly-unsaturated fatty acids (arachidonic acid).
- F2 isoprostanes are removed from the body with urine.
